Package 'shazam'
| Title: |
Immunoglobulin Somatic Hypermutation Analysis |
| Description: |
Provides a computational framework for analyzing mutations
in immunoglobulin (Ig) sequences. Includes methods for Bayesian
estimation of antigen-driven selection pressure, mutational
load quantification, building of somatic hypermutation (SHM)
models, and model-dependent distance calculations. Also
includes empirically derived models of SHM for both mice and
humans. Citations: Gupta and Vander Heiden, et al (2015)
<doi:10.1093/bioinformatics/btv359>, Yaari, et al (2012)
<doi:10.1093/nar/gks457>, Yaari, et al (2013)
<doi:10.3389/fimmu.2013.00358>, Cui, et al (2016)
<doi:10.4049/jimmunol.1502263>. |
| Authors: |
Mohamed Uduman [aut],
Namita Gupta [aut],
Susanna Marquez [aut, cre],
Julian Zhou [aut],
Nima Nouri [aut],
Noah Yann Lee [aut],
Ang Cui [ctb],
Jason Vander Heiden [aut],
Gur Yaari [aut],
Steven Kleinstein [aut, cph] |
| Maintainer: |
Susanna Marquez <[email protected]> |
| License: |
AGPL-3 |
| Version: |
1.2.1.999 |
| Built: |
2025-02-07 06:32:36 UTC |
| Source: |
https://bitbucket.org/kleinstein/shazam |
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